Search results for "model [hadronization]"
showing 10 items of 1415 documents
Una nota sobre crisis y estratificación social
2012
La crisis actual ha creado un colectivo específico de personas en riesgo de caer en la exclusión social. Básicamente se trata de jóvenes e inmigrantes. En ambos casos se agrava cuando coincide con escasa formación y cargas familiares. Su futuro es más que incierto y cabe predecir que la sociedad tardará en encontrarles acomodo pues ni el actual modelo productivo, ni el que pueda sustituirlo, van a generar empleo para esos perfiles. Pero es que tampoco el actual modelo de protección social, lento en sus reacciones y sesgado en favor de currícula laborales estables y continuados, les dará cobertura suficiente. La E.P.A. nos permite una aproximación al problema desde el ejemplo de la Comunidad…
Towards a General Definition of Modeling
2010
What is a model? Surprisingly, in philosophical texts, this question is asked (sometimes), but almost never – answered. Instead of a general answer, usually, some classification of models is considered. The broadest possible definition of modeling could sound as follows: a model is anything that is (or could be) used, for some purpose, in place of something else. If the purpose is “answering questions”, then one has a cognitive model. Could such a broad definition be useful? Isn't it empty? Can one derive useful consequences from it? I'm trying to show that there is a lot of them.
ShRNA-mediated knock-down of CXCL8 inhibits tumor growth in colorectal liver metastasis.
2018
CXCL8 belongs to proinflammatory chemokines that are predominantly involved in neutrophil chemotaxis and degranulation. Several studies have suggested that secretion of CXCL8 from cancer cells have a profound effect on tumor microenvironment. In this study, in continuation to our previous work of understanding the global picture of invasion related genes in colorectal liver metastases, we clearly show an up-regulation of CXCL8 expression in the tumor cells at the invasion front as compared to the tumor cells in the inner parts of the tumor. Furthermore, ShRNA mediated down-regulation of CXCL8 resulted in inhibition of cell proliferation, viability and invasion in vitro and a near complete g…
COX-2 expression in chondrosarcoma: A role for celecoxib treatment?
2010
Chondrosarcomas are resistant to conventional chemo- and radiotherapy. A subset of chondrosarcomas arises secondarily in the benign tumour syndromes enchondromatosis (EC) and multiple osteochondromas (MO), and prevention of tumour development would greatly improve prognosis. We therefore investigated the effect of selective COX-2 inhibition on chondrosarcoma growth. COX-2 expression was studied in central- and peripheral cartilaginous tumours. The effect of COX-2 inhibition was assessed in four high-grade chondrosarcoma cell lines using celecoxib and NS-398 treatment. COX-2 activity (prostaglandin E-2 (PGE(2)) ELISA) and cell viability were measured. The (prophylactic) effect of celecoxib o…
Vammaisuuden sukupuolittuneet ja sortavat diskurssit : yhteiskunnallis-diskursiivinen näkökulma vammaisuuteen
2007
Väitöstyössään Marjo-Riitta Reinikainen tutkii kriittisellä otteella tavanomaista arkista puhetta vammaisuudesta. Huomion kohteena ovat vammaisuudelle ja vammaisena olemiselle teksteissä annetut merkitykset, erityisesti näiden sukupuolittuneet sekä vammaisten sortoa ja syrjintää tuottavat ja ylläpitävät muodot. Reinikaisen tutkimissa teksteissä vammainen mies kuvataan usein oletettujen positiivisten ominaisuuksiensa, kykyjensä ja saavutustensa kautta, kun taas vammainen nainen kuvataan pikemminkin menetystensä ja puutteidensa kautta. – Kun vammaispuhetta tarkastellaan sukupuolinäkökulmasta, käsitykset vammaisuudesta ja vammaisena olemisesta näyttäytyvät selvästi sukupuolittuneina. Tosin san…
Identifying the Neurocognitive bases of creativity to increase human and computational creativity
2022
En esta Tesis Doctoral se ha identificado la estructura neurocognitiva que sustenta la creatividad humana a partir del análisis conjunto de más de 800 referencias bibliográficas que muestran las investigaciones más importantes realizadas hasta la fecha. Sobre la base de esta estructura, se ha identificado un paradigma neurocognitivo de la creatividad humana y se ha propuesto un modelo neurocognitivo del proceso creativo. Finalmente, también se ha propuesto un paradigma creativo neurocognitivo computacional y se ha diseñado la estructura de un sistema computacional creativo, basado en una estructura multiagente. La investigación que se ha realizado sobre el tema hasta la fecha es muy especia…
Trans-Contextual Model Predicting Change in Out-of-School Physical Activity: A One-Year Longitudinal Study
2021
The aim of the current study was to test the long-term predictive validity of the trans-contextual model in accounting for variance in adolescents’ out-of-school physical activity measured by self-report and accelerometer based-devices over a one-year period. Secondary school students ( N = 265) aged 11 to 15 years completed a three-wave survey on two occasions in time, spanning a one-year interval, measuring perceived autonomy support in physical education (PE), peer and parent autonomy support in leisure-time, autonomous and controlled motivation in PE and leisure-time, attitude, subjective norms, perceived behavioural control, intention, and out-of-school physical activity both by sel…
Quantitative Approximation Properties for the Fractional Heat Equation
2017
In this note we analyse \emph{quantitative} approximation properties of a certain class of \emph{nonlocal} equations: Viewing the fractional heat equation as a model problem, which involves both \emph{local} and \emph{nonlocal} pseudodifferential operators, we study quantitative approximation properties of solutions to it. First, relying on Runge type arguments, we give an alternative proof of certain \emph{qualitative} approximation results from \cite{DSV16}. Using propagation of smallness arguments, we then provide bounds on the \emph{cost} of approximate controllability and thus quantify the approximation properties of solutions to the fractional heat equation. Finally, we discuss genera…
Gradient and Lipschitz Estimates for Tug-of-War Type Games
2021
We define a random step size tug-of-war game and show that the gradient of a value function exists almost everywhere. We also prove that the gradients of value functions are uniformly bounded and converge weakly to the gradient of the corresponding $p$-harmonic function. Moreover, we establish an improved Lipschitz estimate when boundary values are close to a plane. Such estimates are known to play a key role in the higher regularity theory of partial differential equations. The proofs are based on cancellation and coupling methods as well as an improved version of the cylinder walk argument. peerReviewed
An evolutionary Haar-Rado type theorem
2021
AbstractIn this paper, we study variational solutions to parabolic equations of the type $$\partial _t u - \mathrm {div}_x (D_\xi f(Du)) + D_ug(x,u) = 0$$ ∂ t u - div x ( D ξ f ( D u ) ) + D u g ( x , u ) = 0 , where u attains time-independent boundary values $$u_0$$ u 0 on the parabolic boundary and f, g fulfill convexity assumptions. We establish a Haar-Rado type theorem: If the boundary values $$u_0$$ u 0 admit a modulus of continuity $$\omega $$ ω and the estimate $$|u(x,t)-u_0(\gamma )| \le \omega (|x-\gamma |)$$ | u ( x , t ) - u 0 ( γ ) | ≤ ω ( | x - γ | ) holds, then u admits the same modulus of continuity in the spatial variable.